Figure 1: The affinity model of thymocyte selection ... tolerance owing to incomplete presentation of endogenous self antigens on MHC class II molecules of mTECs. Taken together, it may be ...

Figure 2: The role of antigen and costimulation in TCR triggering ... according to the progression model, to their functional diversification. Thus competition serves two important functions ...

DNA is open and accessible, while the action of an epigenetic editor turns it into functionally inactive DNA, which is closed ...

在一项新的研究中，来自邓迪大学靶向蛋白降解中心和勃林格殷格翰公司的研究人员开发出一种突破性的小分子药物——“蛋白降解剂（protein degrader）”。相关研究结果发表在2024年9月20日的 Science 期刊上，论文标题为 ...

Chemokine Tumor model or challenge microorganism Results Ref. Coadministration of chemokine with antigen: coadministration of pDNA or recombinant protein encoding chemokines with antigen CCL5 ...

Zeng and the team fabricated DoriVac vaccines in which different numbers of CpG strands were spaced at 2.5, 3.5, 5, or 7 nanometers apart from each other on one face of the square block, and a model ...

By Pooja Toshniwal Paharia New research reveals how common dietary proteins like bovine serum albumin (BSA) or ovalbumin (OVA ...

特斯拉Model Y定位于为中型SUV，同时也是特斯拉的第五款量产车型，其基于Model 3平台开发而来，因此设计风格上与Model 3十分相似。尽管外观很相似，但是车身尺寸方面，Model Y确实要比Model 3要实在很多，Model Y比Model 3长了56mm、宽了71mm、高了181mm、轴距长了15mm ...

"However, when the MHC-II is missing a crucial piece called the invariant chain (Ii), it can present larger, misfolded self-antigens, called neoself-antigens, to T cells." Given that ...

The new version 5.0 of the AI model EDEN™ features a novel toxin antigen predictor, is trained on an expanded dataset and includes an advanced protein prediction featureThe launch will expectedly impr ...

Summary of the research: This study revealed that T cells can discriminate between self- and neoself- antigens, and that neoself-reactive T cells are involved in causing autoimmune diseases.