Under normoxic conditions HIF is degraded, but under hypoxic conditions or iron restriction HIF is stabilized and can bind specific promoters to drive the expression of genes that are involved in ...

Immunotherapeutic approaches have substantially improved the treatment of patients with advanced malignancies. However, most ...

Therefore, hypoxia is generally associated with more aggressive cancers and poor patient outcomes, as it drives changes that make tumors more resistant to treatment. This well-stablished paradigm is ...

After the recent death of an American woman who used the Sarco sparked controversy, one journalist has revealed what it was ...

The partnership aims to expedite the creation of precise treatments to improve results for solid tumour patients.

Three women were taken to hospital injured after shots were fired from a car in Wolverhampton, West Midlands. Detectives ...

Proponents of the nitrogen hypoxia execution method, which replaces oxygen breathed by an inmate with 100 ... “Clearly it was ...

BRP’s storied Can-Am brand to build motorcycles again, and they’ll be electric ...

Dr. Greg Vigna Many infants with mild neonatal encephalopathy face long-term disabilities, highlighting the need for evidence-based treat ...

Dr Vause told the inquest that 'every second counts' when an unborn child is suffering hypoxia. She suggested the delay was due to the couple's questions around the need for to have general ...

Three women were caught in crossfire when shots were fired from a car in Wolverhampton on Friday night. Police rushed to the ...

Three women were taken to hospital injured after shots were fired from a car in Wolverhampton, West Midlands. Detectives ...