New research presented today at European Committee for Treatment and Research in Multiple Sclerosis 2024 reveals that ...

Natalizumab is a disease-modifying therapy that works by attaching to immune cells and preventing them from moving across the blood-brain barrier and entering the central nervous system.

Evidence is rising in favor of using highly effective DMTs to treat pediatric MS, but with few licensed for pediatric use, it ...

Interferon and natalizumab were initially used less frequently, but their usage equalized over time (OR 0.99 [95% CI 0.92–1.06], OR 0.96 [95% CI 0.86-1.06], respectively). In contrast ...

"The acceptance of the filing of proposed biosimilar natalizumab by the European regulatory authorities means we are a critical step closer to getting this important medicine to the patients who ...

Natalizumab eventually ended up as Tysabri, Biogen’s drug for multiple sclerosis, Actemra (tocilizumab) went to Roche as a treatment for rheumatoid arthritis, and Entyvio (vedolizumab ...

This year, it has been joined by natalizumab (Tysabri; Elan/Biogen-Idec), a humanized antibody against α4 integrin, and most recently, the PEGylated humanized anti-TNF-α antibody fragment ...

Unjustified fears about harm in pregnancy is preventing the use of highly effective medications in women with MS, new ...

This is really important, because there have been case reports of patients experiencing relapses with natalizumab and fingolimod when they've discontinued the medication. That's why it's important for ...

The patient sentiment towards the multiple sclerosis drug Tysabri (natalizumab), which was linked with three cases of progressive multifocal leukoencephalopathy (PML) in July and October of 2008 ...

Patients with high sNfL levels often did not respond well to standard disease-modifying treatments (DMTs) but showed significant benefits from high-efficacy DMTs (HE-DMTs) such as natalizumab ...

New research presented today at ECTRIMS 2024 reveals that initiating monoclonal antibody therapy during childhood, rather than delaying treatment until early adulthood, significantly reduces long-term ...