Increased exon skipping, particularly affecting proteasome-related transcripts, was mediated by elevated serine/arginine-rich splicing factor 6 (SRSF6) levels in T-cell acute lymphoblastic leukemia.

2018 Meetings Abstracts: Fifth AACR-IASLC International Joint Conference: Lung Cancer Translational Science from the Bench to the Clinic January 8–11, 2018; San Diego, CA Proceedings: AACR Annual ...

This study uncovers a role for OSMR in promoting ovarian cancer cell proliferation and metastasis by activating STAT3 signaling and demonstrates the preclinical efficacy of antibody-based OSMR ...

The recognition of DNA as an immune-stimulatory molecule is an evolutionarily conserved mechanism to initiate rapid innate immune responses against microbial pathogens. The cGAS–STING pathway was ...

Abstract. In solid tumors, three main complementary approaches of adoptive T-cell therapies were successively developed: tumor-infiltrating lymphocytes, chimeric antigen receptor engineered T cells, ...

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AbstractBackground:. Some countries have implemented stand-alone human papillomavirus (HPV) testing while others consider cotesting for cervical cancer screening. We compared both strategies within a ...

HBV-induced upregulation of HSPA8 promotes hepatocarcinogenesis by suppressing ferroptosis and stimulating HBV replication, identifying HSPA8 as a potential therapeutic target in liver cancer.

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Genomic biomarker profiling of circulating tumor cells enabled by the MinimuMM-seq assay could be used clinically for early diagnosis, monitoring, and management of patients with multiple myeloma with ...

AACR Journals Blood Cancer Discovery Cancer Discovery Cancer Epidemiology, Biomarkers & Prevention Cancer Immunology Research Cancer Prevention Research Cancer Research Cancer Research Communications ...

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