Receptor activity modifying protein 1 (RAMP1) is an integral component of several receptors including the calcitonin gene-related peptide (CGRP) receptor. It forms a complex with the calcitonin ...

Sensory Stimulation Systems, and GENUS, refer to a noninvasive procedure, i.e., a "digital therapeutic," being developed by Cognito Therapeutics. The company developed a wearable GammaSense ...

A new sensory-friendly swim series will kick off next month for kids and adults with sensory or adaptive needs. They will be able to take a dip in the Roosevelt Park Swim Center’s leisure pool.

Ryan Aston, Standard-Examiner Sensory bags from the Autism Council of Utah have been provided to organizations around Weber County, including the Pleasant View Emergency Center.

In 2018, the United States Food and Drug Administration (FDA) approved Aimovig (erenumab) for the prevention of migraine. Erenumab is the first FDA approved antibody therapeutic against a ...

Sensory systems are composed of receptors that sense the sensory stimuli, brain areas involved in sensory perception and neural pathways that connect them.

Lundbeck advances leadership in migraine with new data at the American Headache Society 67th Annual Scientific MeetingIn a post-hoc analysis of the DELIVER trial, interictal periods were longer ...

A series of pavilions along an abandoned Parisian railway, designed to engage the senses, are among the architectural proposals from students at Architectural Institute Paris.

本研究针对月经性偏头痛 (MM)的发病机制，通过野生型与Ramp1基因敲除小鼠模型，首次揭示雌激素通过RAMP1动态调控三叉神经节 (TG)中降钙素基因相关肽 (CGRP)系统的分子机制。研究发现Ramp1表达与雌激素周期呈正相关，并通过表观遗传修饰影响CGRP信号通路，为开发性别特异性偏头痛治疗方案提供新靶点。

为解决白癜风靶向治疗药物奇缺的临床困境，上海交通大学医学院附属第一人民医院王宏林团队和杭州市第三人民医院许爱娥团队联合攻关，首先对正常和白癜风皮肤进行单细胞联合空间转录组学测序分析，首次发现白癜风皮损中存在常规Ⅰ型树突状细胞（cDC1）-CD8+ T细胞互作，且真皮cDC1特异性高表达CGRP受体CALCRL-RAMP1，提示白癜风真皮cDC1可能接受CGRP信号调控。