Recent advances in understanding the mechanisms of protein aggregation and their physiological consequences have been achieved through chemical biology approaches, such as rationally designed ...

After a decade of persistent effort, researchers have obtained the first complete structure of a bacterial protein with one of the longest folded conformations of any known protein—600 nm in ...

Researchers have discovered previously undetected chemical bonds within archived protein structures, revealing an unexpected complexity in protein chemistry.

Abstract Proteins mediate the critical processes of life and beautifully solve the challenges faced during the evolution of modern organisms. Our goal is to design a new generation of proteins that ...

The part of the virus imaged, called the spike protein, helps the virus attach to and infect human cells, and its structure comes just weeks after the virus’s genome sequence was published.

By changing the physical and chemical structures of a protein, these processes can change their function and even lead them to fail.

Scientists’ Work on Protein Structure, Which Governs All Aspects of Life, Wins Nobel Prize in Chemistry David Baker, Demis Hassabis and John M. Jumper revealed how amino acids shape protein ...

For most proteins, structure is function. The complex three-dimensional shapes that proteins adopt create folds and pockets that can accomplish the remarkably improbable: driving chemical ...

In recent years, models like AlphaFold changed our ability to predict the 3D structure of proteins, offering crucial insights into molecular shape and interaction.