Under normoxic conditions HIF is degraded, but under hypoxic conditions or iron restriction HIF is stabilized and can bind specific promoters to drive the expression of genes that are involved in ...

State attorneys general and U.S. senators have pressed the FDA to take steps to eliminate pulse oximetry’s racial bias, which ...

TRIGGER WARNING* Contains sensitive subject material discussing death and suicide. Is Black Mirror becoming a reality? For ...

The partnership aims to expedite the creation of precise treatments to improve results for solid tumour patients.

Therefore, hypoxia is generally associated with more aggressive cancers and poor patient outcomes, as it drives changes that make tumors more resistant to treatment. This well-stablished paradigm is ...

Dr. Greg Vigna Many infants with mild neonatal encephalopathy face long-term disabilities, highlighting the need for evidence-based treat ...

Immunotherapeutic approaches have substantially improved the treatment of patients with advanced malignancies. However, most ...

Hypoxia arises as tumours grow rapidly ... This well-stablished paradigm is not absolute, however. Recently, Dr. Esteban Ballestar's group at the Josep Carreras Institute has published a study ...

Proponents of the nitrogen hypoxia execution method, which replaces oxygen breathed by an inmate with 100 ... “Clearly it was ...