Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its ...

Emerging data show that immune overactivation, especially through macrophage-driven inflammation, plays a decisive role in worsening COVID-19. Among many inflammatory mediators, lipocalin 2 (Lcn2) has ...

Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.

SARS-CoV-2-infected interstitial macrophages, the scientists have learned, morph into virus producersand squirt out inflammatory and scar-tissue-inducing chemical signals, potentially paving the road ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Kunkalikar, Bhavana. (2023, May 13). Study explores macrophage susceptibility to SARS-CoV-2 virions.

CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses. PLOS Pathogens, 2022; 18 (10): e1010479 DOI: 10.1371/journal.ppat.1010479; ...

The lung-cell type that’s most susceptible to infection by SARS-CoV-2, the virus that causes COVID-19, is not the one previously assumed to be most vulnerable. What’s more, the virus enters this ...

When monocytes differentiate in a Th1 immune environment, the resulting macrophage develops an M1, or classical, activation state. This is in contrast to the M2 activation state, derived in a Th2 ...

Macrophage infiltrate and prognosis in c-erbB-2-overexpressing breast carcinomas. S M Pupa , R Bufalino , A M Invernizzi , S Andreola , F Rilke , L Lombardi , M I Colnaghi , S Ménard Journal of ...