These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

Ago2 differentially regulates oncogenic and tumor-suppressive miRNAs in cancer cells. This discrepancy suggests a secondary event regulating Ago2/miRNA action in a context-dependent manner. We show ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Remnants of transposable elements (TEs) are widely expressed throughout mammalian embryo development. Originally infesting our genomes as selfish elements and acting as a source of genome instability, ...

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imageimageHow ion transport proteins affect tumorigenesis remains poorly understood. Here, comprehensive pan-cancer data mining combined with in silico and functional analyses uncovers a catalogue of ...

imageimageThere are no cellular or molecular biomarkers diagnostic of myalgic encephalomyelitis (also known as chronic fatigue syndrome [ME/CFS]). We find hundreds of blood-based traits are different, ...

Aggressive prostate cancer (PCa) variants associated with androgen receptor signaling inhibitor (ARSI) resistance and metastasis remain poorly understood. Here, we identify the axon guidance ...

Copine-6 is a calcium-sensitive phospholipid-binding protein of the evolutionarily conserved Copine family. In the central nervous system, Copine-6 regulates function of some neurotransmitter ...

imageimageChloride ions are important inducers of salt toxicity in soybean plants. This study identifies GmNPF7.5 as a major contributor to chloride accumulation, and suppressing its expression leads ...