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Given the amino-acid sequence or 3D structure of a protein, how much can we predict about its function using just a desktop computer? The recent explosive growth in the volume of sequence data and ...
Protein structure predictions are bioinformatic analyses that produce predicted protein structures automatically using the protein amino acid sequence.
Abstract Proteins mediate the critical processes of life and beautifully solve the challenges faced during the evolution of modern organisms. Our goal is to design a new generation of proteins that ...
Protein–protein interactions are no longer considered undruggable because of the conceptual and technical advances that allow inhibitors to be generated using rational design principles and ...
When Alphabet announced in 2021 that its AlphaFold AI could predict the structure of almost every known protein, it was a major story, not just in the pharma world, but beyond. Yet, that was far ...
In a study published in Cell Research, a research team has, for the first time, resolved the high-resolution in situ structure of the central apparatus (CA) within the axoneme of mammalian sperm.
Inter-residue communication forms a vast and intricate network that underpins essential biological processes such as catalysis, gene expression, and cell signaling. Allostery, a crucial phenomenon ...
14 天Opinion
Montreal Gazette on MSNThe Right Chemistry: There are skeletons in the Nobel Prize closetThe Nobel Prize is the most significant recognition of a scientist’s work, but it also shines a spotlight that follows the ...
Our data sharing policy The Royal Society of Chemistry believes that where possible, all data associated with the research in a manuscript should be Findable, Accessible, Interoperable and Reusable ...
The official journal of the International Union of Immunological Societies (IUIS) and the most cited in its field, leading the way for research across basic, translational and clinical immunology.
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