1 Department of Pharmacology, Medical Hospital of the University of Cologne, Cologne, Germany 2 Department of Internal Medicine I, Medical Hospital of the University of Cologne, Cologne, Germany 3 ...

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1 Department of Paediatrics, University of Naples Federico II, Naples, Italy and European Laboratory of Food Induced Disease (ELFID), Naples, Italy Background and aims: The genetic load in coeliac ...

Introduction Alcohol use disorders and alcohol related liver disease have a significant adverse impact on individuals, healthcare and society. Although abstinence is highly effective, engagement with ...

Alcohol-associated hepatitis (AH) is the acute deterioration of alcohol-related liver disease (ArLD) with rapid onset or ...

Correspondence to Professor Rohit Loomba, Department of Medicine, University of California San Diego, La Jolla CA 92037, USA; roloomba{at}ucsd.edu Objective Emerging data suggest that a 30% relative ...

In 1989, hepatitis C virus (HCV) was first identified as the infectious agent responsible for human non-A, non-B hepatitis.1 Two decades later, HCV remains a global public health problem with a ...

Objective The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe ...

We would like to offer some critical observations regarding the recent article published on the environmental impact of ...

Anorectal manometry was done in 10 men with chronic radiation proctitis and symptoms of urgency, frequency, and occasional incontinence of faeces. They were compared with 10 asymptomatic age and ...

Introduction Faecal calprotectin is a useful diagnostic assessment tool, providing accurate differentiation of organic bowel disease from functional issues. As with any test, there is a false positive ...

Objective The microbiome contributes to the pathogenesis of inflammatory bowel disease (IBD) but the relative contribution of different lifestyle and environmental factors to the compositional ...