Calixarene - Wikipedia
网页A calixarene is a macrocycle or cyclic oligomer based on a methylene-linked phenols. With hydrophobic cavities that can hold smaller molecules or ions, calixarenes belong to the class of cavitands known in host–guest chemistry .
The synthesis and characterization of giant Calixarenes
网页2019年1月10日 · Calixarenes are cyclic oligomers obtained by condensation reactions between phenols and formaldehyde and usually include up to eight phenolic subunits. Here the authors demonstrate the synthesis...
Calixarene - an overview | ScienceDirect Topics
网页Calixarene is a macrocyclic ligand composed of 4, 6, or 8 phenolic units linked by methylene bridges, known for its ability to encapsulate different ions through specific interactions and conformational properties.
Calixarenes: Generalities and Their Role in Improving the Solubility ...
网页2019年3月5日 · The calixarenes are a family of macrocyclic compounds with a variable number of phenol units linked by methylene bridges in ortho position [33]. The number of units of aromatics can be between 4 and 20, although the calixarenes of 4, 5, 6, 7, and 8 are the most common [34, 35].
Calixarenes: An Introduction - Royal Society of Chemistry
网页2008年1月22日 · Calixarenes was the first book to be published in the `Monographs in Supramolecular Chemistry' series and is also the first complete survey available of this rapidly developing field. It provides a fascinating and lively account of the history, development and applications of calixarenes, which …
Calixarenes: recent progress in supramolecular chemistry for ...
网页Calixarenes make up a fascinating class of macrocycles that find a wide range of biological applications in supramolecular chemistry. Especially in recent years, the anticancer activity of various calixarene derivatives has been reported by many researchers.
Role of Calixarene in Chemotherapy Delivery Strategies
网页2021年6月29日 · Calixarene allows the controlled and localized administration of anticancer drugs, increasing the effectiveness of delivery and consequently decreasing the side effects. Furthermore, due to its extraordinary selectivity, calixarene targets cancer cells, avoids healthy cells damage and reduces side toxicity.
Revisiting Fluorescent Calixarenes: From Molecular Sensors to …
网页Calix [n]arenes (n = 4, 5, 6, 8) are “chalicelike” phenol-based macrocycles that are among the most fascinating and highly studied scaffolds in supramolecular chemistry. This stems from the functional and tunable diversity at both their upper and lower rims, their preorganized nonpolar cavities and preorganized ion-binding sites, and their ...
Angewandte Chemie International Edition - Wiley Online Library
网页Calixarenes (CAs) represent the third generation of supramolecular hosts and one of the most widely studied macrocyclic scaffolds. They offer almost unlimited structural possibilities due to their ease of modification, providing a tremendous molecular library as a material basis for diverse biomedical applications.
Protein–Calixarene Complexation: From Recognition to Assembly
网页2022年6月6日 · Calixarene complexation enables protein encapsulation, not merely side chain encapsulation. Cocrystal structures of sulfonato-calix[8]arene with cytochrome c or Ralstonia solanacearum lectin (RSL) provide evidence of encapsulation, with multiple calixarenes masking the same protein.