Choosing a Drug to Prevent Malaria | Malaria | CDC
网页2024年7月18日 · FDA has announced a temporary shortage of Mefloquine Hydrochloride, one of the medications used to prevent malaria. Clinicians who would like to discuss alternative options for specific populations can contact the CDC malaria hotline/clinical consult service at malaria@cdc.gov, or call Monday–Friday, 9 am–5 pm EST 770-488-7788 or …
Chloroquine - Wikipedia
网页Chloroquine has been used in the treatment and prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae. It is generally not used for Plasmodium falciparum as there is widespread resistance to it.
Chloroquine, an Anti-Malaria Drug as Effective Prevention for ...
网页2021年3月15日 · Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections - PMC. Journal List. Front Cell Infect Microbiol. PMC8006394. As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or …
The host targeting effect of chloroquine in malaria - PMC
网页2020年8月18日 · Chloroquine has a clear anti-inflammation and anti-cytokine effect during malaria. It may accumulate in any low-pH organelle such as lysosomes in immune cells due to its weak base property and increases pH.
Chloroquine and hydroxychloroquine in the treatment of malaria …
网页2020年9月8日 · Chloroquine (CQ) and Hydroxychloroquine (HCQ) have been commonly used for the treatment and prevention of malaria, and the treatment of autoimmune diseases for several decades. As their new mechanisms of actions are identified in recent years, CQ and HCQ have wider therapeutic applications, one of which is to treat viral infectious diseases.
Pharmacology of Antimalarial Drugs, Current Anti-malarials
网页2019年2月28日 · Therapeutic Indications for Malaria. Chloroquine is one of the most successful and widely used medications and with obvious health precautions, saving countless lives from malaria since the 1940s. The drug was for several decades the antimalarial of choice because it was effective, well tolerable, safe, and low cost.
Malaria - Diagnosis & treatment - Mayo Clinic
网页2023年2月9日 · The most common antimalarial drugs include: Chloroquine phosphate. Chloroquine is the preferred treatment for any parasite that is sensitive to the drug. But in many parts of the world, parasites are resistant to chloroquine, and the drug is no longer an effective treatment.
Drug Resistance in the Malaria-Endemic World | Malaria | CDC
网页Chloroquine-resistant P. falciparum first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted, with the exception of Central America west of Panama ...
Chloroquine: Uses, Interactions, Mechanism of Action - DrugBank …
网页Chloroquine is an antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
Dosing Recommendations for Prevention and Treatment of Malaria
网页Dosage Recommendations for Prevention and Treatment of Malaria. Chloroquine base 5 mg/kg body weight base by mouth, up to 300 mg once weekly (equivalent to 7.5 mg/kg body weight chloroquine phosphate). Start 1–2 weeks before leaving, take weekly while away, and then take once weekly for 4 weeks after returning home.