Irinotecan - Wikipedia
网页Irinotecan is a topoisomerase inhibitor [9] —it blocks the topoisomerase I enzyme, resulting in DNA damage and cell death. [8] Irinotecan was approved for medical use in the United States in 1996. [8] It is on the World Health …
Irinotecan Uses, Side Effects & Warnings - Drugs.com
网页2024年4月3日 · Irinotecan is used to treat cancers of the colon and rectum. It is usually given with other cancer medicines. Irinotecan may also be used for purposes not listed in this medication guide.
Irinotecan - StatPearls - NCBI Bookshelf
网页2023年7月21日 · Irinotecan is a medication used to manage and treat a variety of solid tumors. It is in the DNA topoisomerase I inhibitor class of drugs. Also known as CPT-11, irinotecan is used adjunctively with other therapeutic agents against colorectal cancer as a first- or second-line treatment.
Irinotecan (Intravenous Route) Description and Brand Names ...
网页2024年10月1日 · Descriptions. Irinotecan injection is given together with other medicines (eg, 5-fluorouracil, leucovorin) to treat patients with metastatic cancer (a cancer that has already spread) of the colon or rectum.
Irinotecan Hydrochloride - NCI - National Cancer Institute
网页Irinotecan hydrochloride is a type of chemotherapy drug called a topoisomerase I inhibitor. It causes breaks that cannot be repaired in the DNA of cells. This stops the growth of cancer cells and other rapidly dividing cells and causes them to die.
Irinotecan: Uses, Interactions, Mechanism of Action ...
网页Irinotecan is a topoisomerase inhibitor used to treat metastatic carcinoma of the colon or rectum and pancreatic adenocarcinoma.
Irinotecan Side Effects: Common, Severe, Long Term - Drugs.com
网页2024年6月1日 · Learn about the side effects of irinotecan, from common to rare, for consumers and healthcare professionals.
Irinotecan (Campto) | Cancer information - Cancer Research UK
网页Irinotecan is a type of chemotherapy. It is a treatment for bowel cancer. Find out about how you have it, possible side effects and other important information.
Irinotecan (Intravenous Route) Side Effects - Mayo Clinic
网页2024年10月1日 · Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur: More common. Anxiety. black, tarry stools. blood in the urine or stools.
Irinotecan Monograph for Professionals - Drugs.com
网页Irinotecan (Monograph) Brand name: Camptosar. Drug class: Antineoplastic Agents. VA class: AN900. Chemical name: (S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano [3′,4′:6,7]indolizino [1,2-β]quinolin-9-yl ester [1,4′-bipiperidine]-1′-carboxylic acid trihydrate monohydrochloride. Molecular formula: C 33 H 38 N 4 O 6 •HCl•3H 2 O.