Neutrophil extracellular traps - Wikipedia
网页Neutrophil extracellular traps (NETs) are networks of extracellular fibers, primarily composed of DNA from neutrophils, which bind pathogens. [2] Neutrophils are the immune system's first line of defense against infection and have conventionally been thought to kill invading pathogens through two strategies: engulfment of microbes and secretion ...
Neutrophil extracellular traps in immunity and disease
网页2017年10月9日 · Neutrophil extracellular traps (NETs) protect against infection, in particular by large pathogens, but they are also implicated in the pathology associated with a growing number of...
Neutrophil extracellular traps in homeostasis and disease
网页2024年9月20日 · Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are renowned for their propensity to expel decondensed chromatin embedded with inflammatory proteins.
Recognition and control of neutrophil extracellular trap ... - Nature
网页2024年8月14日 · How MICL recognizes and autoregulates the formation of neutrophil extracellular traps is explored in mouse models and human patients where disease severity is associated with aberrant...
Neutrophil extracellular traps: from physiology to pathology
网页2021年10月14日 · The release of web-like DNA structures named neutrophil extracellular traps (NETs) constitutes an important mechanism by which neutrophils prevent pathogen dissemination or deal with microorganisms of a bigger size.
Neutrophil Extracellular Traps - PMC - National Center for ...
网页Neutrophil extracellular traps (NETs) are made of a network of extracellular strings of DNA that bind pathogenic microbes. Histones and several neutrophil granule proteins associated with the DNA framework damage entrapped microorganisms.
Neutrophils’ Extracellular Trap Mechanisms: From Physiology to ...
网页2022年10月25日 · Neutrophils are an essential part of the innate immune system and the first line of defense against invading pathogens. They phagocytose, release granular contents, produce reactive oxygen species, and form neutrophil extracellular traps (NETs) to fight pathogens.
Neutrophil Extracellular Trap Formation: Physiology, Pathology…
网页2019年8月14日 · Neutrophil extracellular traps (NETs), a unique DNA framework decorated with antimicrobial peptides, have been in the scientific limelight for their role in a variety of pathologies ranging from cystic fibrosis to cancer. The formation of NETs, as well as relevant regulatory mechanisms, physiologica …
Identification of neutrophil extracellular trap-related genes in ...
网页2024年9月24日 · Neutrophil extracellular traps (NETs) have been proven to be tightly linked to AD. This project attempted to identify hub genes for AD based on NETs. Gene expression profiles of the training set and validation set were downloaded from the Gene Expression Omnibus (GEO) database, including non-demented (ND) controls and AD …
Neutrophil, neutrophil extracellular traps and endothelial cell ...
网页2023年1月11日 · 1. Neutrophils show increased lifespan and impaired migration, both of which promote organ damage. 2. Neutrophils and neutrophil extracellular traps (NETs) induce pro-inflammatory and pro-angiogenic ...