Oxetane - Wikipedia
网页Oxetane, or 1,3-propylene oxide, is a heterocyclic organic compound with the molecular formula C 3 H 6 O, having a four-membered ring with three carbon atoms and one oxygen atom. The term "an oxetane" or "oxetanes" refer to …
Oxetanes: Recent Advances in Synthesis, Reactivity, and Medicinal ...
网页2016年9月15日 · Oxetanes, as strained cyclic ethers, present a fascinating combination of stable motifs for medicinal chemistry and reactive intermediates for further synthesis. These features make them attractive motifs for an ever-increasing range of applications in the chemical sciences.
网页2016年4月28日 · ABSTRACT: The four-membered oxetane ring has been increasingly exploited for its contrasting behaviors: its influence on physicochemical properties as a stable motif in medicinal chemistry and its propensity to …
Oxetane | C3H6O | CID 10423 - PubChem
网页Oxetane | C3H6O | CID 10423 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Oxetane Synthesis via Alcohol C–H Functionalization
网页2023年7月18日 · Oxetanes are strained heterocycles with unique properties that have triggered significant advances in medicinal chemistry. However, their synthesis still presents significant challenges that limit the use of this class of compounds in practical applications.
网页Oxetanes are strained four-membered heterocycles containing an oxygen atom, which are receiving attention in drug design given their metabolic stability, rigidity and hydrogen-bond acceptor...
Oxetanes: Recent Advances in Synthesis, Reactivity, and
网页2016年10月12日 · This review takes an overview of the literature for the synthesis of oxetane derivatives, concentrating on advances in the last five years up to the end of 2015. These methods are clustered by strategies for preparation of the ring and further derivatization of preformed oxetane-containing building blocks. Examples of the use of …
Oxetanes are back - Nature Catalysis
网页2023年8月23日 · Oxetanes are strained four-membered heterocycles containing an oxygen atom, which are receiving attention in drug design given their metabolic stability, rigidity and hydrogen-bond acceptor...
Oxetane - an overview | ScienceDirect Topics
网页Oxetanes are an important four-membered cyclic ether principally occupied as an attractive structural motif in diverse medicinally and bioactive molecules. Apart from this, oxetane serves as a powerful IM in advanced synthesis of a …
Oxetanes as Versatile Elements in Drug Discovery and Synthesis
网页Small but powerful: In recent years oxetanes have received newly gained attention in medicinal chemistry and by the synthetic community since it has been found that the introduction of an oxetane unit in the molecular scaffold of a compound can significantly modify its properties.
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