Poloxamer 407 - Wikipedia
网页Poloxamer 407 is a hydrophilic non-ionic surfactant of the more general class of copolymers known as poloxamers. Poloxamer 407 is a triblock copolymer consisting of a central hydrophobic block of polypropylene glycol flanked by two hydrophilic blocks of polyethylene glycol (PEG).
A review of poloxamer 407 pharmaceutical and pharmacological ...
网页Poloxamer 407 formulations led to enhanced solubilisation of poorly water-soluble drugs and prolonged release profile for many galenic applications (e.g., oral, rectal, topical, ophthalmic, nasal and injectable preparations) but did not clearly show any relevant advantages when used alone.
A Review of Poloxamer 407 Pharmaceutical and Pharmacological ...
网页2006年11月11日 · This article addresses the physical and pharmaceutical properties of Poloxamer 407, specifies possible applications of this copolymer, emphasises development pathways to promote drug delivery (e.g., Poloxamer 407 combination with other polymers, inclusion of liposomes or nanoparticles in a Poloxamer 407 thermoreversible gel...).
Poloxamer 407: What is it and where is it used? - Drugs.com
网页2024年9月16日 · Poloxamer 407. Medically reviewed by Drugs.com. Last updated on Sep 16, 2024. Excipient (pharmacologically inactive substance) What is it? Poloxamers are polymers used for drug delivery as formulation excipients.
Kolliphor® P 407 Geismar | Poloxamers - BASF Pharma
网页Kolliphor® P 407 is supplied as white to slightly yellowish, coarse-grained powder with a waxy consistency. It is soluble in water, ethanol (95%) and isopropanol. It is insoluble in ether, paraffin and fatty oils. Benefits. HLB value between 18-23.
Poloxamer 407 (Surfactant): Cosmetic Ingredient INCI
网页Poloxamer 407 is a polyoxyethylene polymer and a hydrophilic non-ionic surfactant. It is made up of two blocks of hydrophilic polyethylene glycol on either side of a central hydrophobic polypropylene glycol block. In cosmetic and personal products, poloxamer 407 is used as an emulsifier and solubilizer.
网页The Kolliphor® P 407 is a block copolymer that is a synthetic copolymer of ethylene oxide and propylene oxide represented by the following chemical structure: Where the a and b blocks have the following values: Appearance. Kolliphor® P 407 is produced as a white to almost white prill/powder. CAS Number. 9003-11-6. Molecular Weight.
Mucosal Applications of Poloxamer 407-Based Hydrogels: An …
网页2018年9月12日 · Poloxamer 407, also known by the trademark Pluronic ® F127, is a water-soluble, non-ionic triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) between the two hydrophilic units of polyoxyethylene (POE). Poloxamer 407-based hydrogels exhibit an interesting reversible thermal characteristic.
Poloxamer 407 purified, non-ionic 9003-11-6 - MilliporeSigma
网页Poloxamer 407 is a water-soluble, non-ionic surfactant with low toxicity and good solubilizing capacity. This triblock copolymer is composed of a hydrophobic residue of polyoxypropylene (POP) flanked by two hydrophilic units of polyoxyethylene (POE).
An Overview on Thermosensitive Oral Gel Based on Poloxamer 407
网页2021年8月12日 · A temperature-sensitive polymer system comprising poloxamer 407 (PX) and poly(acrylic acid) (PAA), which showed relatively stable viscosity values at low shear rates and decreased viscosity at higher shear rates due to partial disruption of the polymer interactions, was studied.
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